A novel determination of curcumin via Ru@Au nanoparticle decorated nitrogen and sulfur-functionalized reduced graphene oxide nanomaterials
By Kotan, Gul and Kardas, Faruk and Yokus, Ozlem Aktas and Aky[i without dot]ld[i without dot]r[i without dot]m, Onur and Saral, Hasan and Eren, Tanju and Yola, Mehmet Lutfi and Atar, Necip
Published in Anal. Methods
The Royal Society of Chemistry
2016
Abstract
We report the synthesis of Ru@Au nanoparticle involved l-cysteine functionalized reduced graphene oxide (rGO) composites (NSrGO/Ru@AuNPs). The nanocomposites were characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS) and X-ray diffraction (XRD). The electrochemical determination of curcumin (CR) has been studied using square wave voltammetry (SWV) on a glassy carbon electrode (GCE) modified with NSrGO/Ru@AuNP composites (NSrGO/Ru@AuNPs/GCE). The effective surface areas (ESAs) of the rGO/GCE and NSrGO/Ru@AuNPs/GCE were calculated to be 347 cm2 mg-1 and 1289 cm2 mg-1, respectively. These results show that the electrochemical surface area of the NSrGO/Ru@AuNPs/GCE is 3.71 times higher than that of the rGO/GCE. The developed method was also applied successfully for the determination of CR in plasma and the linearity range of CR was 0.001-0.1 nM with a detection limit of 2.0 [times] 10-13 M.